i was referring to the radiator valves, its a different valve set up altogether, the individual valve allows hot water to circulate through your radiator leaving you with the ability to turn off said radiator, and still allowing the primary loop to pass through said valve to the next radiator without affecting flow rates.
each valve has a small screw or alan key that adjusts and balances the system changing the flow through the primary loop.
if the primary loop, has too low or high a flow rate, it will upset the boiler. combi boilers get more unhappy about this than system boilers. all to do with temperature differences over flow and return.
i have fitted many combi boilers on one pipe systems (spain likes them) never had a problem with new installs because the system is clean, however i had plenty of calls to similar problems as yours, or a plumber had put in a new boiler and ch had stopped working. plumber hadnt flushed pipes. the fault was always sludge in system.
hope that helps a bit
shaun