1. Turn off boiler. Make sure all radiator valves are at least partly open, but don't touch the lockshields unless you really have to.
2. Relieve system pressure via a radiator bleed valve. Close bleed valve afterwards.
3. Locate lowest drain off point. This may be a radiator valve or valves with a drain off built in, or one or more drain cocks (see Screwfix 12232 to see what it looks like). Drain cocks my be internal, or if you are very lucky outside at ground floor level. Push hose pipe over open end of drain cock and run other end outside / to drain. End of hose must be lower than drain cock, and hose should not rise between ends. I usually put a jubilee clip over the hose at drain cock end, and plenty of old towels on floor beneath. Open drain cock.
4. If there is no drain cock, you can drain from a convenient (ground floor, near door or drain) radiator:
4a. Turn off both radiator valves, counting lockshield 1/8 turns as previously.
4b. Get ready with some shallow dishes and old towels.
4c. Undo the compression nuts holding the valves to the radiator tails and empty contents of radiator into dishes / towels. Water could be very dirty, so steer clear of carpets etc.
4d. Very slightly slacken the compression nut holding the incoming pipe to one of the valves.
4e. Pull valve off radiator tail and turn 90 degree to face you. Re-tighten compression nut holding valve to pipe.
4f. Attach hose pipe to open face of valve using lots of insulating tape. Make sure it is reasonably secure.
4g. Loads of old towels underneath.
4h. Open valve and system will start to drain.
5. As you have a combi you will have no motorised valves to worry about, but if wasn't a combi you would need to manually open them.
6. Starting upstairs, go round the radiators opening the bleed valves. As each is opened you may hear the hiss of air being drawn in. If water comes out, shut valve and wait a few moments until the system has drained a bit more.
7. Once water has stopped flowing from the hose, the system is drained.
8. If it were me I'd flush the system through with clean water a couple of times:
8a. Make sure all radiator bleed valves are closed.
8b. If you had no drain cock and did as 4 above, I'd reattach the valves to that radiator rather than risk the makeshift joint coming apart. Then fill and re-drain as above. Maybe a couple of times.
8c. If you have a drain cock, just close it.
8d. Refill the system, opening the bleed valve on each radiator (from bottom up) to make sure the radiator is full of water.
8e. Make sure that the boiler pressure doesn't go over 1.5 bar while doing this. Best to let some water in, shut off the inlet valve, bleed the radiators until pressure drops, open inlet valve and repeat.
9. After final drain, refill adding inhibitor as you did for adding cleaner.