Even on a well designed open heating system, there will be air released somewhere.
When water is heated up it will create micro bubbles of air at heat source (boiler) & these air bubbles tend to travel around the system until they hit a low pressure point, usually the first radiator, typically upstairs, or a towel rail. When the system cools down again, it absorbs air again from the expansion tank & vent & feed pipe & so the cycle continues. An auto vent on the boiler will not remove the air bubbles as they are in movement & suspended in the water.
Best solution if you have gas or oil heating is to get it changed to a sealed system if the system is decent order & no weeps. It can't absorb & release air because it is not open to atmosphere.
Do check you do not have auto vents letting air suck into system.
There is also air grabbing devices such as Flamco air vent which catches the air & then auto vents it. It is simply a wide vessel, which in itself grabs air plus it has lots of tiny cylindrical stainless steel bits to catch micro bubbles & then an auto vent on top.