Thanks for your reply, Chris. My responses to your points:
We need to supplement the UFH because much of the floor areas in the ensuites will be taken up with shower trays, sanitary ware/units. Also we need to dry towels because there may be one or two people in each bedroom serviced by its ensuite.
You shouldn't need to if UFH is designed & used correctly as the whole thermal mass of the floor will be heated by the rooms around it, with warm air being drawn in from adjacent rooms when the extract is on.
Towel drying via electric elements in the rails, why not?
Good point about scale, I'll check with JIS. Their towel rails are guaranteed for 25 years
but they won't be any more immune to scale than the rest of the fittings fed by the DHW loop. We will have a "scale buster" type of conditioner on the cold water supply, and probably a second one after the circulating pump before the hot water returns to the cylinder, but who knows how well these water scale inhibitors work? We are in a hard water area, Thames Water. The temperature will be much lower than a radiator circuit which should help, but of course we can't add inhibitor. If we hold max temp to about 60 deg maybe not too much of the problem (?), no worse than a combi secondary anyway, I guess.
None of the water conditioner work, it is not so much the scale but the oxygenated water that will be a problem depending on the grade of s/steel used it can still be effected but it is the accumulation of air in them that would see them stop working unless they are fully vented.
The Comfort pump I would use in its temperature control mode, not Autoadapt. It would therefore be on whenever the DHW temperature in the loop drops below the target temp (50 deg?). The pipes of the loop are being insulated with 30mm thick phenolic foam (conductivity 0.025 W/(m.K)). At 60 deg C I estimate the heat loss at less than 6kWhr per day, even including the towel rail loop extensions and tails.
That seems very low for the losses from the rails as well, your hot water will need to be no all day to make these up & stop the system dropping below 60 - 65 flow / 55 return.
Not sure what you mean by "Pump what need to be sized to suit the installed index circuit" please can you explain?
What I meant is that the circulator would need to be sized correctly as it will now need to over come the frictional resistants from the towel rails & pipework as well as supplying the correct amount of water as this will be carrying the heat now needed.
There is only one secondary loop.