Could you please come and explain that to some of my landlords?
Joking aside, it is a good time to be taking on commercial property. A year or two ago, the rules changed, and now landlords have to pay rates on empty buildings. Before that change, they could hold out for a higher rent- it wasnt actually costing them anything to let a building sit empty.
It doesnt apply so much to the big estates, which tend to be owned by massive property investment funds, but if you see a small individual unit, or a shop in a secondary trading area (ie not main shopping centre) you can pick them up quite cheaply.
The only word of warning is - don't invest too much on fitting out unless you have a long lease. If the property market picks up in a few years time when your lease expires, or your rent review is due, the boot will be on the other foot, and if the landlord sees that you have invested a lot on fit-out, it gives him lots of leverage on the negotiation.